1. Examples include tetanus toxin and the herpes simplex, rabies, and polio viruses. 2. Such toxins as the botulinum and tetanus toxins work by targeting the SNARE components. 3. The tetanus toxin initially binds to peripheral nerve terminals. 4. Tetanus toxin and botulinum toxin affect neurotransmitter release.5. Tetanus toxin causes violent spastic paralysis by blocking the release of ?-aminobutyric acid ( GABA ).6. Tetanus toxin is a potent neurotoxin.7. In the 1910s he demonstrated that natural and synthetic suprarenin had the ability to neutralize diphtheria and tetanus toxins . 8. In 1993, Langer's team put the tetanus toxin into microscopic spheres of biodegradable polymer which would release it steadily. 9. Ricin is several orders of magnitude less toxic than botulinum or tetanus toxin , but the latter are harder to come by. 10. Tetanus toxin is generated in living bacteria, and is released when the bacteria lyse, such as during spore germination or vegetative growth.
Mobile